Research Focus

USC Michelson Center CSI-Cancer is aimed at integrating patient, model system, and high-content single cell data to translate clinically observed correlations into a mechanistic understanding of the physical and biological underpinnings of cancer dynamics. The organizing framework of the physical dynamics of cancer at the lab will focus on the spatial distributions and temporal evolution of the disease at the cellular, human, and population scale.

Three complementary research projects, supported by one shared resource core, address the laboratory’s aims of:

developing a quantitative description of the transition between limited and disseminated cancer,

demarcating the complexity and alterations over time of a cancer in all its phases,

describing the temporal evolution of disease in patients with poor prognosis vs favorable prognosis.

Join the Team

For prospective graduate students, we are affiliated with Dornsife CLAS, Keck School of Medicine, and Viterbi School of Engineering. Please apply to the following PhD programs:

Dornsife Molecular Biology:

Dornsife Computational Biology and Bioinformatics

Keck: Programs in Biomedical and Biological Sciences (PIBBS),

Viterbi Computer Science

Viterbi Aerospace and Mechanical Engineering

For postdoctoral fellows and other inquiries, email pkuhn1[]at[]usc[]dot[]edu

For current USC undergraduates, apply to join the CURE program at cure.usc.edu to do research in the lab. Further, consider enrolling in BISC 410: Applications of Molecular Biology to Medicine taught by professors Kuhn and Hicks. (Note: BISC410 is full for fall 2019. Please email us and let us know why you wanted to take this class.)

Summer research opportunities at CSI-Cancer are also available to all college and high school students through the BUGS program

Collaborations

CSI-Cancer has built and will continue to build a larger collaborative network to disseminate its capabilities and to collaborate on evolving physical sciences concepts that could address specific challenges as part of the organizing framework within the institute and the scientific community at large. Solving the problems associated with the currently imperfect performance of our therapeutic interventions and making real improvements in patient outcomes requires the understanding of the disease as a dynamical system undergoing constant transitions in both time and space and using tools from biology, physics, mathematics, and computer science

The collaborative network shows the various disciplines and specialties working with us

USC Schools and Departments, Research Institutions, Clinics, Foundations, and Industry partners

Directions to CSI-Cancer

We are located on the 3rd floor of Michelson Hall at the University Park Campus of USC: 1002 Childs Way, Los Angeles, CA 90089. While metered street parking is available on the streets ($1 per hour), the nearby spots are generally occupied. Parking permit for one of the USC parking structures can be arranged prior to the day of arrival, please contact the laboratory. Access into Michelson Hall is card-controlled, please arrange for someone to meet you in the lobby downstairs.