Structure of the EphA3 receptor/ephrin-A5 Ligand Complex
The Kuhn laboratory at the Bridge Institute at the University of Southern California and the Sanford-Burnham Medical Research Institute (La Jolla, CA) report the first crystal structure of the ligand binding domain of human EphA3 receptor in complex with its preferred ligand, ephrin-A5. EphA3 receptor, a member of the receptor tyrosine kinase family, is a …
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